抽象的：

目的：维生素D由于其非增殖性，非血管生成特性，这是一些癌症，结肠，肺和前列腺等癌症的标志改变了寻找维生素D缺乏，VDRGP和乳腺癌协会的研究方向。方法：对VDR基因多态性诱导无症状，预期预血尿女性（20至40岁）。FOK1和APA1的PCR -RFLP已完成。血清维生素D水平在补充之前和之后进行两次。结果：妇女（N-294）最低为20岁，最大年龄为40岁。Shapiro-Wilk正常测试完成了。数据是非参数的。还计算了平均值±SD（30.6±6.01）中位数和IQR。中位年龄为30岁，IQR年龄为10.33，维生素D基线的平均值±SD为9.87±7.29和7（6.63），为IQR。fok1和Apa1基因在人群中都很普遍。 The p-values i.e. 0.58 & 0.259 showed that there was no significant mean difference observed in vitamin D at baseline level for Fok1 PCR and Apa1 PCR. Similarly, Fok1 & Apa1 RFLP showed no statistically significant difference in the mean values of vitamin D at baseline level; p-values were 0.759 and 0.44 respectively. Conclusions: VDR genotypes vary widely. There was equal distribution of folk1 and Apa1 genes. The important observation was the absence of homozygous group in Apa1. In comparison to other studies both Fok1 and Apa1 were not significantly related to vitamin D deficiency, which concludes that VDR gene polymorphism is not significantly related to breast cancer.